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What is CBD?

CBD, otherwise known as cannabidiol is one of the most well-known chemical compounds found inside the cannabis plant aside from THC. Unlike THC, cannabidiol does not give users the psychoactive effect associated with marijuana.

Both CBD and THC are cannabinoids. However, they are altogether different substances.

There are about 113 known cannabinoid compounds found in the cannabis hemp plant. Other known cannabinoids are:

Cannabidiol (CBD)
Cannabinol (CBN)
Cannabigerol (CBG)
Tetrahydrocannabinol (THC)
Tetrahydrocannabinolic acid (THCA)
Cannabidiolic acid (CBDA)
Cannabichromene (CBC)
Cannabicyclol (CBL)
Tetrahydrocannabivarin (THCV)
Cannabidivarin (CBDV)
Cannabivarin (CBV)

Full Spectrum vs Isolate

Full spectrum CBD hemp oil, contains every cannabinoid present in the cannabis plant. This means cannabidiol, cannabicyclol, tetrahyrdocannabivarin, and cannbichromevinaric acid, to name a few. Different cannabinoids contain various potential benefits that can address a wide variety of ailments, both on their own and in conjunction with one another, and with CBD.

CBD isolate is simply purified CBD that has been extracted from the hemp plant and isolated from all other cannabinoids.

CBD and The Endocannabinoid System

CBD’s effects all come down to the body’s endocannabinoid system, which is a network of 5-HT receptors that are activated and play a role in maintaining homeostasis in the body. Homeostasis affects pain, mood, and appetite among others other factors. CBD interacts with the receptors of the endocannabinoid system, predominantly the CB1 and CB2 receptors that are found mainly in the brain and immune cells. While the body already has its own set of cannabinoids, introducing CBD to the body enhances the efficacy of the endocannabinoid system.

While CBD does not actually bind directly with these receptors, it interacts with them indirectly and modulates many non-cannabinoid receptors and ion channels. The endocannabinoid system determines how the body processes and utilizes cannabinoids.

How Does CBD Take Effect in the Body?

CBD’s therapeutic effect on the body occurs in several ways including the following:

5-HT1A Serotonin: CBD has been shown to activate 5-HT1A serotonin receptors in the body, which can help alleviate anxiety, reduce nausea and vomiting, regulate appetite and improve sleep. They’re found in the central and peripheral nervous systems and stimulate many different chemical messages, which can either produce an excitatory or inhibitory response.

GPR55 Protein Receptors: cannabidiol acts as an antagonist to GPR55 protein receptors. By blocking it, CBD can help to hinder bone reabsorption associated with osteoporosis and modulate blood pressure. It can also help to reduce the spread of cancerous cells throughout the body as GPR55 has been associated with the proliferation of cancer cells.

PPARs: CBD plays a role in activating PPARs, which have been associated with reducing the effects of Alzheimer’s Disease and even have anti-cancer effects. PPARs are located on the surface of the cell’s nucleus. By activating the PPAR-gamma receptor, CBD has an anti-proliferative effect on cancer cells. The activation of PPAR-gamma also diminishes amyloid-beta plaque, which is associated with the onset of Alzheimer’s disease. This is why CBD can be an effective agent for Alzheimer’s patients. Further, diabetics can find much use for CBD and its activation of PPAR receptors because they regulate genes involved in insulin sensitivity.

TRPV1 Receptors: CBD binds to TRPV1 receptors in the endocannabinoid system, which helps to reduce pain and inflammation, and regulate body temperature.

The Benefits of CBD

How to Take CBD

Frequently Asked Questions

What is CBD

To define CBD simply, it is the acronym for cannabidiol and is one of the most well known chemical compounds found inside the cannabis plant aside from THC. Unlike THC however, cannabidoil does not produce the psychoactive effect that has become commonly associated with marijuana nor many of the other symptoms. In other words, they are both cannabinoids but one is distinctly separate from THC meaning that they are different substances.

Is CBD Legal

Although CBD comes from the cannabis plant family like its intoxicating cousin compound THC, you will not feel a “high” or psychoactive effect from CBD. Although there are tiny trace amounts of THC in most CBD products, the amount is so low that it is functionally impossible to get intoxicated from it. Therefore, CBD is legal to purchase and own across the United States.

What are some CBD Side Effects

Mild side effects from CBD are usually reported by users who took relatively high doses. Drowsiness or grogginess was the most common of these side effects. More than this, however, the most important consideration before taking CBD is to determine how it interacts with any drugs you are currently on. CBD may interfere with the way your drug regimen is working, so it’s critical that you have a conversation with your doctor to confirm that it’s appropriate to begin using CBD on your own.

Does CBD make you high

No — CBD will not get you “high” like the other famous chemical compound found in cannabis (THC). However, just because it doesn’t give you a “body buzz” or intoxicating high does not mean that you won’t feel an effect from taking CBD. The most commonly reported effects include a general sense of well-being or anxiety reduction, or a calm clarity of focus. Regardless, there is no intoxication involved. The World Health Organization has determined that there is no potential for abuse in terms of CBD usage.

What does CBD feel like

CBD affects everyone differently, but don’t go into your first CBD dose expecting to feel a “body high” or effect similar to THC-rich cannabis. It simply doesn’t work that way. THC binds directly to your CB1 and CB2 receptors; CBD, on the other hand, acts as a sneaky indirect agonist of cannabinoid receptors. That all means, in layman’s terms, that you won’t “feel” a prominent effect from taking CBD.

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